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Tosoh: The Chemistry of Innovation
Ion Exchange Chromatography
HPLC Columns
Anion Exchange
TSKgel BioAssist Q
TSKgel DEAE-2SW
TSKgel DEAE-3SW
TSKgel DEAE-5PW
TSKgel DEAE-NPR
TSKgel DNA-NPR
TSKgel DNA-STAT
TSKgel QAE-2SW
TSKgel Q-STAT
TSKgel SAX
TSKgel Sugar AXG
TSKgel Sugar AXI
TSKgel SuperQ-5PW
Cation Exchange


TSKgel Q-STAT columns are packed with 7 and 10µm hydrophilic non-porous resin particles of which the surface consists of an open access network of multi-layered anion exchange groups. The innovative bonding chemistry, combined with a relatively large particle size, results in a respectable loading capacity and a low operating pressure, making these columns suitable for all HPLC and FPLC systems.

Applications for the TSKgel Q-STAT columns include the separation of: proteins, peptides, low molecular weight nucleic acids, aggregates and charge isomers of monoclonal antibodies, PEGylated proteins, oligo DNA, and siRNA.

 

Product Attributes:

 Matrix: hydrophilic polymer
 Particle size (mean): 7 and 10µm
 Pore size (mean): non-porous
 Functional group: quaternary ammonium
 Counter ion: Cl
 pH range: 3.0 - 10.0
 Static binding
 capacity 
(mg BSA/
 g dry gel):

ca. 25 (7µm)
ca. 20 (10µm)

 Small ion capacity: 270ueq/g dry gel
 pKa: 10.5



Literature:

Technical Presentation -- High Speed and High Resolution Anion Exchange Chromatography for Biological Samples on Non-Porous Packings 

Operating Conditions and Specifications

Product Overview -- TSKgel Q-STAT Anion Exchange Column

 

 Applications


The protein mixture was completely separated within 1 minute and with higher resolution on the
TSKgel Q-STAT column in comparison to the monolithic WAX column. 



 


 
P/N
Description
Particle
size
Housing material ID
(mm)
Length
(cm)
0021960

TSKgel Q-STAT

10µm
Stainless Steel 3 3.5
0021961

TSKgel Q-STAT

7µm
Stainless Steel 4.6 10


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Frequently asked questions -- IEC

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Tosoh Bioscience Japan, Shiba, Minato-Ku, Tokyo 105-8623, Japan TEL:+81-3-5427-5118 FAX:+81-3-5427-5198 Email:hlc@tosoh.co.jp