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Tosoh: The Chemistry of Innovation
Reversed Phase Chromatography
Reversed Phase Columns
Silica-based Columns
8nm Monomeric RP Silica
10nm Monomeric RP Silica
2µm Super Series RP Silica
Specialty RP Silica
High Throughput RP Silica
Polymer-based Columns


The silica-based TSKgel reversed phase product line consists of eleven stationary phases designed for the analysis of low molecular weight analytes such as:

  • pharmaceutical drugs
  • forensic compounds
  • derivatized amino acids
  • carbohydrates
  • steroids, lipids, fatty acids

Depending on their molecular weight, peptides may be analyzed with the same silica-based RPC columns, while proteins require a larger pore size column (20-30 nm ).

TSKgel silica packings are spherical with uniform pore sizes of 10, 14, 15, or 25 nm bonded with a monomeric or polymeric layer of octadecyl, octyl, cyano, trimethylsilyl or phenyl groups.  Several of the stationary phases are subsequently capped with trimethylsilyl groups by a proprietary method that deactivates the unreacted but accessible silanol groups.

 

10nm Monomeric
RP Silica

8nm Monomeric
RP Silica

2µm Super
Series
RP Silica

Specialty RP Silica

This latest generation of highly pure 10nm pore size silica is the foundation for sophisticated bonding chemistries.
These are the preferred columns for demanding separations of polar (ODS-100V) and small MW basic compounds (ODS-100Z).


The 10nm pore size makes this column type ideal for samples smaller than 6,000 Da molecular weight. This product line features exhaustively endcapped 80Ts columns for basic solutes and the moderately endcapped 80TM columns for peptide separations.

The “Super Series” provides higher efficiency and improved resolution over conventional columns packed with 3 and 5μm particles.
Pore size of 14nm makes the “Super Series” columns most suitable for samples with molecular weight below 10,000 Da molecular weight.

TSK-GEL specialty RP silica columns were developed to provide optimum separation for:

 


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Tosoh Bioscience Japan, Shiba, Minato-Ku, Tokyo 105-8623, Japan TEL:+81-3-5427-5118 FAX:+81-3-5427-5198 Email:hlc@tosoh.co.jp