Toyopearl PPG-600 (polypropylene glycol) has the second highest hydrophilicity of the HIC ligands offered by TBL. It has been optimized for the purification of monoclonal antibodies and is used as an intermediate purification or polishing step. It has extremely good capacity and recovery for mAbs.

Structure:

Hydrophobicity:

Ether < PPG < Phenyl < Butyl < Hexyl
(least to most)

Product Attributes:

Pore size (mean):  75nm  Particle size (mean):  65µm (M-grade)   Pressure rating:  0.3 MPa  Shipping buffer:  20% ethanol  pH stability:  1-13

Literature:

Catalog - Process Media, Hydrophobic Interaction Chromatography

Product Overview -- Toyopearl PPG-600M, for Hydrophobic Interaction Chromatography of Monoclonal Antibodies, Hydrophobic Proteins and Pegylated Targets

Technical Presentation -- Purification of monoclonal antibodies using new pore size optimized HIC resins

 

P/N Description Container size Particle size 0021301 Toyopearl PPG-600M 25mL 40-90µm 0021302 Toyopearl PPG-600M 100mL 40-90µm 0021303 Toyopearl PPG-600M 1L 40-90µm 0021304 Toyopearl PPG-600M 5L 40-90µm